Simvastatin belongs to a group of medicines known as HMG-CoA reductase inhibitors. View complete list of side effects. This means that both … The risk is greater in people taking more than 80mg of simvastatin per day, older than 65, females, with uncontrolled hypothyroidism, or kidney disease. Simvastatin … It can raise triglyceride levels and may increase your risk of liver damage. Simvastatin is also indicated in some genetic lipid disorders (such as heterozygous familial hypercholesterolemia) in adolescents aged 10 to 17 meeting certain criteria. Follow your doctor's dosing instructions very carefully. Last updated on Oct 5, 2020. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. It's used to lower cholesterol if you've been diagnosed with high blood cholesterol.It's also taken to prevent heart disease, including heart attacks and strokes.. Simvastatin belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins.". Get emergency medical help if you have any of these signs of an allergic reaction to simvastatin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Statins lower the amount of ‘bad cholesterol’ (low density lipoprotein or LDL-cholesterol) and ‘fat’ (triglyceride) in the blood as well as increase the amount of ‘good cholesterol’ (high density lipoprotein or HDL-cholesterol). Crestor, which is the brand name for rosuvastatin, and simvastatin are both cholesterol-lowering drugs. Generic Name: simvastatin (SIM va sta tin) Used in the treatment of hyperlipidemia. Simvastatin belongs to a group of medicines called lipid-lowering medicines. Simvastatin does not reduce the cholesterol and triglycerides that come from fatty food. Your doctor may occasionally change your dose to make sure you get the best results. May increase liver enzymes (increases of up to three times the upper normal limit have been reported). The dosage needs to be individualized but higher dosages (ie, 80 mg/day) should not be used unless they are shown to be tolerated without causing muscle pain. People … Gay, Lesbian Adults Often Miss Out on Cholesterol Meds. Use effective birth control to avoid pregnancy while you are taking this medicine. Simvastatin is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors. Do not breast-feed while you are taking this medicine. It is metabolized by hepatic cytochrome P450 (CYP3A4) enzymes and thus has significant drug interactions with other CYP3A4 inhibitors . Atorvastatin (Lipitor) and simvastatin (Zocor) belong to a class of medications known as statins, which are considered to be first-choice medications for treating high cholesterol. It belongs to a group of drugs known as " statins … Many drugs can interact with simvastatin. Do not take extra medicine to make up the missed dose. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. It reduces levels of bad cholesterol (Low-Density Lipoprotein, or LDL) and triglycerides in the blood while increasing the level of good … Call your doctor for medical advice about side effects. Statins reduce low-density lipoprotein, or LDL levels (bad cholesterol) and triglycerides and increase levels of high-density lipoprotein, or HDL (good cholesterol) in the blood. It does this by blocking the action of a certain enzyme (called HMG-CoA reductase) which your body needs to make the fats. Never take simvastatin in larger amounts, or for longer than recommended by your doctor. Simvastatin is also used to reduce high levels of lipids in people with elevated cholesterol levels. To start off, people susceptible to side effects from the regular usage of simvastatin often belong to one of the following categories: Pregnant women, and breast-feeding … Simvastatin works by reducing bad (LDL) cholesterol made by the liver and raises the good (HDL) cholesterol. Adverse reactions may occur with both drugs, and are generally dose-related for both. Consult your doctor for more details. Ezetimibe have synergetic effects when co-administered with simvastatin. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Some side … Last updated on Nov 2, 2020. Version: 18.01. atorvastatin, Xarelto, Lipitor, fenofibrate, rosuvastatin, Crestor, ezetimibe, pravastatin, ramipril, Zetia. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Simvastatin is not suitable for people who are allergic to simvastatin, or any of the excipients. Simvastatin may also be used to prevent certain types of heart problems in patients with risk factors for heart problems. Simvastatin belongs to the drug class known as HMG-CoA reductase inhibitors, also called statins. Simvastatin belongs to a group of drugs called HMG-CoA reductase inhibitors, also known as statins, which block an enzyme in the body called HMG-CoA reductase. Indications Simvastatin Normon is indicated in: treating coronary cardiopathy and/or hyperlipidemia. Take once daily in the evening and avoid large quantities of grapefruit juice. Store at room temperature away from moisture, heat, and light. Ezetimibe have synergetic effects when co-administered with simvastatin. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The dosage of simvastatin does not need adjusting in mild-to-moderate kidney disease. Both simvastatin and pravastatin belong to the same class of cholesterol-lowering drug. Simvastatin is a prescription medication used to treat high cholesterol, high triglycerides, and disease of the heart and blood vessels. Simvastatin belongs to a group of medicines called statins.. Regular blood tests are needed (after 4 weeks of therapy then periodically thereafter) to determine the effect of simvastatin on lipids and other factors (such as liver function). People considered at increased risk of a heart event include those with diabetes, a history of stroke or a similar event, with pre-existing heart disease, or with peripheral vascular disease. Thus, co-administration of these drugs can increase their serum levels, potentially leading to adverse effects. Simvastatin is a prodrug, which means it is converted into its active beta-hydroxyacid form, after administration. It works to reduce the amount of cholesterol in the blood by blocking an enzyme that is needed to make …
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